Research Areas
Coral Resilience Genetics
We use cutting-edge genomic approaches to understand how corals naturally resist devastating diseases like White Band Disease and adapt to thermal stress. Our genome-wide association studies have identified specific genetic markers that predict disease resistance, enabling precision conservation approaches.
Key Discoveries:
- Disease resistance has a polygenic basis with 10 genomic regions involved
- As few as 10 genetic variants can predict coral disease resistance with high accuracy
- Resistant corals use unique immune pathways different from other animals
- Thermal tolerance genes show population structure across coral ranges
This work directly supports coral restoration by helping nurseries select the most resilient coral genotypes for reef rebuilding projects.
Coral Microbiome Characterization
Corals host extraordinarily diverse microbial communities containing both beneficial symbionts and harmful pathogens. We use metagenomics, machine learning, and experimental approaches to understand these complex relationships and identify the key players in coral health and disease.
Research Approaches:
- Machine learning identification of coral pathogens
- Microbiome manipulation using antibiotics and quorum sensing inhibitors
- 16S rRNA sequencing to profile bacterial communities
- Network analysis of microRNA-microbe interactions
Our work has identified multiple candidate pathogens within bacterial families including Vibrionaceae and Flavobacteriaceae, while revealing the importance of beneficial bacteria in coral health.
Conservation Solutions
We bridge basic research with conservation action by working directly with coral restoration organizations. Our genetic tools help coral farmers identify the most disease-resistant and thermally tolerant coral genotypes for large-scale restoration projects.
Conservation Applications:
- Genetic screening for coral nursery operations
- Disease resistance testing for restoration projects
- Collaboration with coral restoration organizations
- Development of molecular assays for field use
We work with coral restoration organizations where thousands of genetically-screened corals are being used to rebuild reefs.